Molecular Cell Biology
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MicroDNAs and Transcriptional Regulation
Synthetic "microDNAs (MIDs)"is a new class of ~ 20-25 nucleotide-long DNAs capable of repressing the activity of the target gene at the level of transcription by mechanisms that have not …
Received 04 November 2009 08:33 UTC; Posted 04 November 2009
Posted to: Cancer, Genetics & Genomics, Molecular Cell Biology
Remarks on the number of tubulin dimers per neuron and implications for Hameroff-Penrose Orch OR
Stuart Hameroff has wrongly estimated that a typical brain neuron has 107 tubulin dimers and wrongly attributed this result to Yu and Baas, J. Neurosci. 1994; 14: 2818-2829. In this letter we sho…
Received 13 October 2009 09:35 UTC; Posted 14 October 2009
Posted to: Molecular Cell Biology, Neuroscience
Limusaurus and bird digit identity
Limusaurus is a remarkable herbivorous ceratosaur unique among theropods in having digits II, III and IV, with only a small metacarpal vestige of digit I. This raises interesting questions regard…
Received 06 October 2009 03:05 UTC; Posted 06 October 2009
Posted to: Developmental Biology, Genetics & Genomics, Molecular Cell Biology, Evolutionary Biology
Mammalian cells in culture actively export specific microRNAs
The discovery of microRNAs (miRNAs) as a new class of regulators of gene expression has triggered an explosion of research, but has left many unanswered questions about how this regulation works an…
Received 04 September 2009 02:06 UTC; Posted 04 September 2009
Posted to: Molecular Cell Biology
Inhibition of Acid Phosphatase Enzyme Activity in the Presence of Noncrystalline Calcium Phosphate and Nanocrystalline Calcium Apatite: a Preliminary Study
BackgroundOur bones are remodelled repeatedly during life. A new and “healthy” bone tissue replaces the old one. Accordingly, the bone degrading cells, the osteoclasts, prefer old and fatigued …
Received 20 August 2009 11:52 UTC; Posted 20 August 2009
Posted to: Chemistry, Molecular Cell Biology
Multivalent ligands of CD22 for targeting of B cells
Multivalent ligands of CD22 for active targeting of B cells. Mary O’Reilly, Wei Hsu Chen, Gladys Completo, Ying Zeng, Satoshi Futakawa and Cory Rillahan and James C. Paulson, Departments of Chemica…
Received 04 August 2009 23:44 UTC; Posted 05 August 2009
Posted to: Biotechnology, Cancer, Chemistry, Immunology, Molecular Cell Biology
Can Vision Exist Without Somatosensation?
The interconnection between vision and somatosensation is already well-established and is further supplemented by the evolutionary link between eyes and photoreceptors, and the functional connectio…
Received 16 July 2009 14:23 UTC; Posted 17 July 2009
Posted to: Molecular Cell Biology, Neuroscience
Technical Note: The Use of RNA-interference as a Tool to Find Proteins Involved in Melanosome Formation or Transport
Melanosomes are lysosome-related organelles that produce and transport the pigment melanin within melanocytes. Mutations in proteins required for melanosome transport and formation lead to a range …
Received 10 July 2009 18:38 UTC; Posted 14 July 2009
Posted to: Molecular Cell Biology
Sugar-based synthesis of Tamiflu and its inhibitory effects on cell secretion
Tamiflu is currently the most effective drug for the treatment of influenza. But the unmet supply and side effects of this drug demand urgent solutions. In this article, a practical synthesis of Ta…
Received 19 June 2009 16:47 UTC; Posted 22 June 2009
Posted to: Chemistry, Molecular Cell Biology
MIF-AMPK cascades
Withdrawn for publication
Received 11 June 2009 21:04 UTC; Posted 12 June 2009
Posted to: Molecular Cell Biology, Pharmacology
